The medical representatives are the primary contributors to the extraordinary growth of the Indian pharmaceutical industry, which has
a 9.5% annual growth rate. Medical representatives are the backbone of pharmaceutical companies and play a difficult role in advertising and delivering products or services to customers as they operate in the field, collecting feedback, resolving issues, and sensing market conditions. The study aims to increase the engagement and productivity of medical representatives and, in turn, assist the pharma industry in retaining their employees for growth by analyzing the factors affecting their work life. This study examines the relationship between work quality and job satisfaction among medical representatives in the pharmaceutical industries in Salem and Erede districts. To meet the study’s objective, a perceptual survey was conducted by collecting data from 161 medical representatives working in Salem and Erode districts using a structured questionnaire and analyzing the data using statistical tools, including reliability, ANOVA, correlation, and regression. The research contributes to formulating a policy that encourages the retention of medical representatives and boosts their productivity in the pharmaceutical industry.